This species was first isolated from peach juice by Sanfelice in 1894 ( Mitchell and Perfect, 1995 Jain et al., 2013). Therefore, a database of skeletal cryptococcosis cases should be created.Ĭryptococcosis, formerly known as torulosis, European blastomycosis, or Busse-Buschke disease, is caused by Cryptococcus neoformans ( C neoformans). Dissemination was irrespective of immune status and required combination therapy, and dissemination carried a worse prognosis. We found that immune abnormality is a risk factor but does not predict mortality these observations are due to recent Cryptococcus neoformans var gattii (CNVG) outbreaks ( Chaturvedi and Chaturvedi, 2011). This systematic review examined all cases published between April 1977 and May 2013 with regard to the factors associated with this disease, including patient sex, age, and epidemiological history affected sites clinical symptoms underlying diseases laboratory tests radiological manifestations and delays in diagnosis, treatment, follow-up assessments, and outcomes. However, limited information is available regarding its clinical features, treatment, and prognosis. Skeletal cryptococcosis, an aspect of disseminated cryptococcal disease or isolated skeletal cryptococcal infection, is a rare but treatable disease.
Department of Orthopaedics, Tianjin Medical University General Hospital, Tianjin, China.Heng-Xing Zhou †, Lu Lu †, Tianci Chu, Tianyi Wang, Daigui Cao, Fuyuan Li, Guangzhi Ning and Shiqing Feng *
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